基本情况
朱东建,教授,博士,硕士生导师,1983年出生,2014年7月毕业于中国科学院大学(中国科学院化学研究所)有机化学专业,现任食品与生物工程学院副院长,食品与营养专业硕士点负责人。
近年来主要讲授的课程
有机化学,有机化学实验,食品生物化学。
主要研究领域
食品有害物质和功能成分检测;分子荧光探针构建与应用。
近年来主持的科研项目
1. 基于半花菁的新型比率荧光探针的构建及其线粒体靶向成像研究,国家自然科学基金地区科学基金项目。
2. 新型香豆素骨架的构建及其近红外比率荧光探针的设计、合成与细胞成像研究,广西自然科学基金重点项目,2019GXNSFDA185003。
3. 双ICT和元素取代协同构筑新型香豆素类近红外比率荧光探针及其线粒体靶向成像,广西自然科学基金面上项目,2024GXNSFAA010380。
4. 新型近红外比率荧光探针的构建及其对农产品中重金属的分析研究,广西自然科学基金面上项目,2018GXNSFAA281166。
5. 基于半花菁的线粒体比率荧光探针的构建及其可视化成像研究,广西自然科学基金青年基金项目,2017GXNSFBA198178。
代表性论文
1. Aishan Ren, Lige Qiao, Kechun Li, Dongjian Zhu*, Yuzhen Zhang*, Thiol-chromene click reaction-triggered mitochondria-targeted ratiometric fluorescent probe for intracellular biothiol imaging, Analytical and Bioanalytical Chemistry, 2024.
2. Biao Wang, Dongjian Zhu*, Yuhao Xiong, Yun Ye*, Ying Jiang*, Wei Xie, Aishan Ren*, A Reaction-based Ratiometric Fluorescent Probe with Large STOKES Shift for Cu2+ in Neat Aqueous Solution, Journal of Fluorescence, 2024.
3. Aishan Ren, Wenqin Yao, Wei Xie, Dongjian Zhu*, A novel reaction-based ratiometric fluorescent probe with large Stokes shift for the detection of Hg2+ in river sample, Journal of Molecular Structure, 2024, 1298, 137035.
4. Aishan Ren, Wenqin Yao, Dongjian Zhu*, A mitochondrion-targeted fluorescent probe based on ESIPT phthalimide for the detection of Hg2+ with large Stokes shift, Analyst, 2023, 148, 5882-5888.
5. Dongjian Zhu, Wenqin Yao, Aishan Ren*, A Reaction-Based ESIPT Fluorescent Probe for the Detection of Hg2+ with Large Stokes Shift, Journal of Fluorescence, 2023.
6. Wenqin Yao, Dongjian Zhu*, Yun Ye, Biao Wang, Wei Xie, Aishan Ren*, A novel colorimetric and ratiometric fluorescent probe for detection of Cu2+ with large stokes shift in complete aqueous solution, Journal of Molecular Structure, 2023, 1278, 134970.
7. Dongjian Zhu*, Shilei Jiang, Wei Zhao, Xiaowei Yan, Wei Xie, Yuhao Xiong, Sujuan Wang, Wen Cai, Youjun Gao, Aishan Ren*, A novel ratiometric fluorescent probe for sensitive and selective detection of Cu2+ based on Boranil derivatives, Inorganica Chimica Acta, 2021, 524: 120438.
8. Aishan Ren, Dongjian Zhu*, Yanghe Luo, A novel Boranil-based turn-on fluorescent probe for imaging of biothiols in living cells, Journal of Molecular Structure, 2020, 1209: 127914.
9. Dongjian Zhu*, Xiaowei Yan, Aishan Ren*, Wei Xie, Zhenhua Duan, A novel colorimetric and ratiometric fluorescent probe for cysteine based on conjugate addition-cyclization-elimination strategy with a large Stokes shift and bioimaging in living cells, Analytica Chimica Acta, 2019, 1058: 136-145.
10. Dongjian Zhu*, Xiaowei Yan, Aishan Ren*, Wen Cai, Zhenhua Duan, Yanghe Luo, Modulation of ICT and PET processes in boranil derivatives: a ratiometric fluorescent probe for imaging of cysteine, Analytical Methods, 2019, 11: 2579-2584.
11. Aishan Ren, Dongjian Zhu*, Xing Zhong, Yuhao Xiong, Zhenhua Duan, A novel fluorescent turn-on probe for imaging biothiols based on SNAr substitution-skeletal rearrangement strategy, Analytical Methods, 2019, 11: 262-267.
12. Aishan Ren, Dongjian Zhu*, Wei Xie, Xingcun He, Zhenhua Duan, Yanghe Luo, Xing Zhong, Mubo Song, Xiaowei Yan*, A novel reaction-based fluorescent probe for sensitive and selectivedetection of Cu2+, Inorganica Chimica Acta, 2018, 476: 136-141.
13. Dongjian Zhu*, Aishan Ren*, Xingcun He, Yanghe Luo, Zhenhua Duan, Xiaowei Yan, Yuhao Xiong, Xing Zhong*, A novel ratiometric fluorescent probe for selective and sensitive detection of Cu2+ in complete aqueous solution, Sensors and Actuators B: Chemical, 2017, 252: 134-141.
14. Dongjian Zhu*, Yanghe Luo*, Liang Shuai, Wei Xie, Xiaowei Yan, Zhenhua Duan, Wen Cai, A hemicyanine-based selective and sensitive colorimetric and fluorescent turn-on probe for Cu2+, Tetrahedron Letters, 2016, 57: 5326-5329.
15. Dongjian Zhu*, Yanghe Luo*, Xiaowei Yan, Wei Xie, Wen Cai, Xing Zhong, A reaction-based fluorescent turn-on probe for Cu2+ in complete aqueous solution. RSC Advances, 2016, 6: 87110-87114.
16. Dongjian Zhu, Lin Xue*, Guoping Li, Hua Jiang*, A highly sensitive near-infrared ratiometric fluorescent probe for detecting nitroreductase and cellular imaging, Sensors and Actuators B: Chemical, 2016, 222: 419-424.
17. Dongjian Zhu, Lin Xue*, Guoping Li, Yanke Che, Hua Jiang*, A turn-on fluorescent probe for detection of hydrogen sulfide in aqueous solution and living cells, Organic Chemistry Frontiers, 2014, 1: 501-505.
18. Dongjian Zhu, Guoping Li, Lin Xue*, Hua Jiang*, Development of ratiometric near-infrared fluorescent probes using analyte-specific cleavage of carbamate, Organic & Biomolecular Chemistry, 2013, 11: 4577-4580.
近年来获得的荣誉
1. 2023年获广西科技大学优秀硕士学位论文指导教师。
2. 2019年获大学生创新创业训练计划项目优秀指导教师。
3. 2018年获贺州学院“身边最美教师”荣誉称号。